Our TTC Timeline

Following is our timeline for TTC. This has a lot of details. I like to keep track of everything I am told at the RE office during treatment cycles, so please ignore if there is anything that may be a little too much for you:

My issues: Low E2, Switched LH/FSH ratio, PCO, Hostile CM, MTHFR, FXIII (V34L), High TH1/TH2, Inflammatory Disease
DH issues: Inconsistent Sperm count, Low Morphology
Married since 2002, 3 Furries (Pebbles, Maya & Gizmo), Started TTC Valentine’s Day 2007

IUI #1  
CD 5-9 100mg Clomid
CD 14 Estrogen 175
CD 15 Trigger
CD 16 IUI (24mil @ 65%)
10/16/10  AF

IUI #2 (B2B)  
CD 5-9 150mg Clomid
CD 12 Estrogen 248 & Trigger
CD 13 IUI (10mil @ 75%)
CD 14 IUI (8mil @ 86%)
11/14/10  AF

IUI #3  
CD 3-7 150mg Clomid
CD 8-9 112.5iu Gonal-F
CD 10 Estrogen 438 & Trigger
CD 11 IUI (9mil @ 77%)
12/11/10 AF

IUI #4 (B2B)  
CD 3-7 150mg Clomid
CD 8-11 112.5iu Gonal-F
CD 12 Estrogen 262 & Trigger & IUI (2mil @ 66%)
CD 13 IUI (7mil @ 65%)
1/8/11  AF

IUI #5  
CD 5-12 175iu Gonal-F
CD 13 Estrogen 417 & Trigger
CD 14 IUI (5mil @ 87%)
7/6 /11 AF

IVF #1 (ICSI & AH) – Microflare Lupron 
9/4/11: CD 1
9/6 Start Gonal-F 2x150iu & Lupron 0.5mg
9/9 u/s (13 follies) & bw (E2: 151, P4: 0.5, LH 1.3, Lining: 10)
9/12 u/s (15 follies) & bw (E2: 628, P4: 0.7, LH 1.7, Lining: 12)
9/14 u/s (15 follies) & bw (E2: 1750, P4: 0.8, LH: 4.1, Lining: 12), Trigger: @10PM
9/15 bw (E2: 2711, P4: 2.7, HCG: 27), Start Prometrium 3xday
9/16 ER @ 10:00 AM (18 eggs, 11 mature, 10 fertilized)
9/19 ET @ 11:30 AM (2 1A 8-cell transferred)
9/20 Start Endometrin 1xday
9/22 bw (E2: 1420, P4: 85)
9/23 no snow babies
9/24 HCG Booster
9/26 bw (E2: 938, P4: 75) & HCG Booster
9/30 BFN
10/3/11 AF

IVF #2 (ICSI & AH) – Antagonist Protocol
3/27/12 CD 1
3/29 E2 24 LH 2.8 FSH 4.5 Start Gonal-F 300iu
4/2 20 Follies E2 225 P4<.5 Lining 9 Ganarelix
4/4 E2 569 P4<.5 Lining 13 LH 1.4
4/6 27 Follies E2 2021 P4 .7 Lining 13 LH 3.7
4/7 Trigger @ 9:30 PM
4/9 ER (16 eggs 12 mature 8 fertilized)
4/12 ET of 3 8 cell embies – no snow babies
4/16 E2 1021 P4 49 HCG Booster
4/20 E2 1771 P4 103
11dp3dt BETA #1 21 E2 2008 P4 166
13dp3dt BETA #2 20 E2 1997 P4 79
15dp3dt BETA #3 34 (dbl 62.7 hrs) E2 2007 P4 97
19dp3dt BETA #4 115 (dbl 54.67 hrs) E2 2587 P4 144
26dp3dt BETA #5 985 (dbl 54.22 hrs) E2 2989 P4 113
5/14 US1 @6w2d HB 133 HCG 4563 (dbl 65.11 hrs) E2 2641 P4 100
5/18 US2 (spotting) @7w0d HB 144
5/23 US3 @7w4d HB 168 HCG 8257 E2 2109 P4 104
5/30 (9w2d) US4 No heartbeat, measuring 7w2d E2 around 1000 P4 66 HCG 11000
6/1/12 D&C @ 9w4d  (D&C revealed no abnormalities, extensive blood panel revealed MTHFR, started Baby Aspirin & Neevo DHA Vitamins)

Oct 2012: Started WeightWatchers (lost 80+ lbs to date) & Exercise 

March 2013: Appt. with Dr. KK (Reproductive Immunologist). Preliminary results: confirmed PCO on ultrasound (not PCOS, waiting on blood tests, but there are definitely 2 cystic ovaries in there), low to no blood flow in Zone 3 around endometrium which is needed for implantation, detected large vessels in uterus which are of concern for vein disease later in live, oddly shaped ovaries (which could impact egg quality), endometrium thin at this point, MTHFR (coupled with Thyroid Scan which is yet to be done, could be cause for implantation failure and pregnancy loss). Starting immediately, put on Metanex, drop Neevo DHA and start Low Carb Diet.

4/5/13: Results from Dr. KK: Elevated TSH, low Vitamin D3, NK Cells elevated, Factor XIII heterozygous mutation, MTHFR 667T mutation. Treatment: Metanx, Synthroid, Metformin, Baby Aspirin, Pre-Natal Vitamins.

5/8/13: Thyroid Meds & Metformin are working. Vitamin D3 still low. Increasing dose to 4000 iu.

IUI #6
CD1 6/1/13
CD8-13 112.5/150iu Gonal-F
CD11 us (3 follies) & bw (E2 78)
CD12 us (perfect, Lovenox is working!!) & bw (chemistry panel, BC, thyroid, Vitamin D all good)
CD13 us (3 follies @ 20, 16, 16) & bw (E2 79?????)
CD17 IUI (10 mil @ 85%)
CD25 us & bw (E2 238, P4 22)
7/1/13 AF

IUI #7
CD1          7/1/13
CD5          225iu Gonal-F
CD9          us (6 follies @ 16, 15, 14, 14, 13, 12) & bw (E2 227, Lining 11.7)
CD11       us (7 follies @ 21, 20, 19, 17, 17, 16) & bw (E2 568, Lining 12)
CD12       Trigger & IUI (25 mil @ 77%)
CD18       us & bw (E2 1605 & P4 58, Lining 14)
7/26/13 AF


11/26/13: New RE (Dr. Uhler @ FCI)
11/27/13: Lab testing performed: E2, FSH, LH, HCG, AMH, TSH, Prolactin, ABO/RH, Rubella, Varicella, HIV 1 & 2, Hep B, Hep C, RPR, CBC, STDs, EMB, Genetic Screening – ALL OK
12/4/13: Saline Sonohysterogram (Results: Normal)
12/12/13: Started Weekly Accupunture treatments at Eastern Healing (Dr. Peter Harvey)
12/13/13: Ultrasound & BW (CBC) – all good
1/7/14: IVF #3 Consult (Antagonist Protocol)

IVF #3 (ICSI & AH) Antagonist Protocol
12/21    CD1
12/25    Start BC
1/13       Stop BC, FCI u/s & bw (E2: 60, P4 looks good)
1/14       Dr. KK bw (NK’s elevated, increase Prednisone to 20mg daily)
1/15       Endometrial Scratching, Start Lovenox 60mg
1/18       Start Stims (Follistim 100 iu, Menopur 150 iu)
1/21       FCI u/s (18 follies, 5 measurable) & bw (E2: 181, P4 0.2, LH 1.45)
1/22       Start Ganirelix
1/23       FCI u/s (21 follies, 8 measurable) & bw (E2: 429, P4: 0.2, LH: 0.809) + Dr. KK u/s (bloodflow @ 0.59/0.60), Lining
8.9mm, Increase Follistim to 125iu & continue Menopur 150iu & Ganirelix 250
1/25       FCI u/s (21 follies, 13 measurable – biggest @ 19.1 & 17) & bw (E2: 1064), Lining: 9.3mm
1/26       FCI u/s (21 follies, 17 measurable – biggest @ 23 & 22.8) & bw (E2: 1414), Lining: 13.2mm
HCG Trigger & final Ganirelix shot @ 8 PM
1/27       Start Z-Pack Antibiotics
1/28       IVF ER (12 eggs, 7 mature, 6 fertilized) with Dr. Marut
1/29       Start Baby Aspirin, Crinone & PIO Oil Shots 1x daily each
1/31       Intralipids Infusion @7.40 AM
2/2         IVF 5-day ET (2 blastocysts transferred (2BB & 3BB) with Dr. Nani, 40mg Lovenox in PM
2/3         No frosties (2 degnerated, 2 stalled), Start 60+40mg Lovenox  & Minivelle patches
2/12       BETA – Negative

 

1 IVF remaining – Not sure when we’ll use it. For now we’re focusing on building our family through Adoption! ❤

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One thought on “Our TTC Timeline

  1. Oh my! I am so sorry to read all of this. I had my fallopian tubes removed and we only had to go through 1 IVF cycle with positive results and it was still hell… My heart goes out to you and your husband for not giving up! You’re probably one of the toughest people I know. Good Luck with your Adoption Journey. I cannot wait for the day your get to hold your Bundle of Joy! ♥

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